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Why More Women Hold Stress? This is the reason!

http://figures.boundless.com/5080294ce4b0423da53fa79c/full/stresssymptoms.gifWhy More Women Hold Stress? This is the reason! - Public opinion says that men and women respond to stress differently. Women are generally more resistant to stress. When facing heavy work pressure, a complex household problems, and other issues that preoccupy and stirring emotions, more women could still think clearly. Chronic stress is more rare in women than in men.

Why so?The answer lies in the female sex hormone, estrogen, which turned out to protect their brain to stress, according to the findings of U.S. researchers. "It could even be another reason why women live longer than men," said the head of research of Professor Zhen Yan of the University of Buffalo.Stress rats.

In their experiments, the research team investigated the molecular mechanisms associated with stress on brain function. For that they are physically confine young male rats and females in small cylindrical cages two hours a day for one week. This action is intended to make the stress of the rats.

To test the animal's short-term memory, the researchers put into the cage a pair of identical objects, followed by a second pair of objects an hour later. The rats with curious objects of unknown investigate it carefully. Three hours later, they were presenting the rats with one object of each pair. Mice spent more time examining objects from the first pair indicates that the animal was remembered from the previous four hours. Rats are more like objects than newer second pair shows she has short-term memory impairment.Weakening the memory.

The researchers tested the animals' memory before and after exposure to stress. In male rats, both before and after a week of exposure to stress, memory performance is very different than in female mice. Memory performance deteriorated in male rats under stress, especially short-term memory.Male rats that had been checked out objects they recognize as if he'd never seen before. Yan said that the stress in male rats lower levels of the neurotransmitter glutamate receptors in the brain called the prefrontal cortex, the area that controls attention, emotion, decision-making and memory performance.

Yan's group found that young female mice was also stressed by physical restraint week, but it did not cause a decrease in their ability to remember and recognize objects they had seen a few hours earlier. This trial found that although stress, female rats had similar levels of glutamate receptors in regions such as the prefrontal cortex before the study. These data support the hypothesis that glutamate receptors play an important role in response to stress.Estrogen as a protector.

Apparently, estrogen prevents the negative effects of stress on the receptor. Male rats were given a synthetic estrogen (estradiol) by researchers react to stress in the same way with female mice. Conversely, when the researchers blocked the effects of estrogen in female mice, memory performance weakened as male rats.

Yan admitted that the result was a new group based on rat studies. However, these findings could be relevant in humans because many cellular functions similar between the two species. "We believe that this mechanism also occurs in humans," he said.

This is especially true on the effects of estrogen in the brain as a stress reducer, which benefits women. If this protection is compromised - for example, the decrease in production during menopause or after childbirth due to hormonal turmoil - it will increase the risk of depression Adding estrogen may help to stabilize the performance of nerve.

However, estrogen can have unwanted effects. In men, excess estrogen can cause feminization. It may be helpful to find a drug that has effects similar to estrogen in the brain without causing any side effects. "It can be a very effective treatment for stress-related problems in men," the researchers said.

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